Strategic Tax Support for Life Sciences Leaders

SPEAK WITH AN EXPERT

Insight, Compliance, and Performance for the Life Sciences Industry

Life science innovators face layered tax complexity from evolving regulatory frameworks, cross-border operations, and margin pressures. We deliver integrated strategies that optimize research and development (R&D) exemptions and incentives, manage transfer pricing, and streamline compliance, helping companies accelerate growth while minimizing risk.

%

of Fortune 1000 Lifesciences companies work with Ryan

Seasoned Tax Experts

Our industry-focused experts turn complex tax challenges into competitive advantages, maximizing savings, improving efficiency, and ensuring compliance.

Multidisciplinary Approach

We bring together consulting, recovery, advocacy, compliance, and technology to deliver fully integrated tax solutions, tailored to each client’s business and industry.

Purpose-Built Platform

Our platform is built for what matters, pairing deep expertise with powerful technology to simplify tax, uncover savings, and keep businesses ahead of change.

The Power of Technology and Expertise—Working as One

We combine deep tax expertise with AI-powered technology to uncover savings across jurisdictions, adapt to regulatory change, and simplify complex reporting, giving businesses clarity, confidence, and control.

Centralized technology tailored to your business

Dedicated experts aligned to performance goals

Real-time insights that drive better decisions

Single point of contact from start to finish

Simplified compliance across all jurisdictions

“On behalf of the Johnson & Johnson Family of Companies, I would like to extend our sincere appreciation for your excellent performance in obtaining the substantial adjustments and refunds of our various Sales/Use and Franchise Tax audit assessments. With a comprehensive knowledge of the law and administrative procedures, you and your associates have successfully obtained adjustments and refunds for Johnson & Johnson companies in the states of California, Florida, New Jersey, Pennsylvania, and Texas.”
Manager, Taxes & Fixed Assets, Johnson & Johnson

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Medical Equipment
We support medical equipment manufacturers with tax strategies designed to manage regulatory complexity, data accuracy requirements, and multijurisdictional obligations across the full product lifecycle.
Tax Pressures Shaping Todayʼs Medical Equipment Landscape
Medical equipment manufacturers operate in a highly regulated environment where tax considerations intersect with product development, supply chains, reimbursement models, and commercialization. Evolving payer structures and regulatory requirements across jurisdictions create layered tax risk that can affect margins and time to market.
Revenue and Reimbursement Complexity
Bundled payments, value-based care models, and varying payer classifications create indirect tax exposure and reporting challenges. These issues are often intensified by jurisdiction-specific tax treatment for durable medical equipment and related technologies.

Regulatory Burden
Federal, regional, and international regulations, often tied to Food and Drug Administration (FDA) timelines and documentation standards, intersect with tax reporting, transfer pricing, and incentive eligibility. Without coordination, these requirements can increase compliance risk and administrative burden.

Data Accuracy and Systems Alignment
Accurate tax outcomes rely on consistent data across R&D, manufacturing, supply chain, and billing systems. Our proprietary platform centralizes tax data to support accurate calculations, exemption management, and regulatory reporting.

Multijurisdictional Compliance
Differing tax rules across regions and countries complicate product classification, exemptions, and cross-border sourcing. We help manufacturers manage these challenges through integrated indirect tax, transfer pricing, and incentive strategies that support compliant global operations.
Pharmaceuticals
We support biotech and pharmaceutical companies with specialized tax strategies that maximize R&D incentives, manage global transfer pricing, and optimize commercialization activities, while ensuring compliance across complex regulatory environments.
Where Life Sciences Companies Encounter Tax Exposure
Life sciences organizations face unique tax challenges from lengthy development cycles, global intellectual property (IP) management, complex regulatory pathways, and cross-border activities. Our integrated approach addresses these exposures while maximizing available incentives.
R&D Incentives
We leverage deep industry expertise to help pharmaceutical businesses maximize federal and regional credits for drug discovery, clinical trials, device engineering, and biotech research.

Global Transfer Pricing
Our experts help pharmaceutical businesses navigate cross-border IP licensing, intercompany pricing, cost-sharing arrangements, and regulatory compliance across multiple tax jurisdictions.

Commercialization and Revenue Treatment
We optimize tax treatment for multijurisdictional product sales, royalty income, milestone payments, and collaborative arrangements while managing permanent establishment implications and indirect tax obligations on cross-border transactions.

Regulatory Complexity
Our experts help life sciences organizations navigate complex tax implications as a result of FDA approval processes, European Medicines Agency (EMA) authorization requirements, good manufacturing practice standards, and international regulatory compliance.
Life sciences leaders face margin pressure, evolving regulatory frameworks, and tax complexity across jurisdictions. We deliver integrated support spanning multijurisdictional compliance, R&D credit optimization, transfer pricing, and indirect tax considerations, using technology to centralize tax data and strengthen accuracy across decentralized systems.

Advanced Solutions for Your
Business’s Toughest Challenges

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Discover How We Help You Pay Only What You Owe—Nothing More

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Frequently Asked Questions

Qualifying activities include:
Clinical trial design and execution
Formulation development and testing
Prototype builds and engineering iterations
Laboratory experimentation
Process development for manufacturing scale-up
FDA or EMA submission preparation
Regulatory testing phases
Drug discovery research, compound screening, and preclinical studies generally qualify. Medical device companies can claim credits for design modifications, materials testing, biocompatibility studies, and human factors engineering. Biotech firms qualify for molecular biology research, genetic sequencing work, and biologic development activities. Activities must involve technological uncertainty, systematic experimentation, and qualified research purposes under applicable tax law.
We prepare technical narratives explaining research objectives, scientific uncertainties addressed, and experimental methodologies employed. We develop contemporaneous documentation systems capturing qualified activities in real time through project tracking, timekeeping integration, and expense allocation methodologies. Our tax experts prepare detailed technical reports supporting credit calculations with documentation of personnel involved, time allocations, supply costs, and contractor expenses. For audit defense, we maintain supporting evidence, including laboratory notebooks, clinical protocols, regulatory submissions, and project management records. This comprehensive approach withstands scrutiny from tax authorities challenging R&D credit claims.
We manage customs duties classification, tariff optimization, and duty drawback opportunities for pharmaceutical ingredients and medical devices. We coordinate VAT and GST compliance across jurisdictions, determining place-of-supply rules for goods shipments and services rendered. For intercompany transactions, we ensure proper value allocation, transfer pricing documentation, and customs valuation support. Our team handles excise taxes on specific pharmaceutical products, free trade agreement documentation for preferential duty treatment, and import/export licensing requirements. This integrated approach addresses both tax compliance and supply chain efficiency for global life sciences operations.

Strategic Tax Support for Life Sciences Leaders

Insight, Compliance, and Performance for the Life Sciences Industry

The Power of Technology and Expertise—Working as One

Centralized technology tailored to your business

Dedicated experts aligned to performance goals

Real-time insights that drive better decisions

Single point of contact from start to finish

Simplified compliance across all jurisdictions

Manager, Taxes & Fixed Assets, Johnson & Johnson

Tax Pressures Shaping Todayʼs Medical Equipment Landscape

Revenue and Reimbursement Complexity

Regulatory Burden

Data Accuracy and Systems Alignment

Multijurisdictional Compliance

Where Life Sciences Companies Encounter Tax Exposure

R&D Incentives

Global Transfer Pricing

Commercialization and Revenue Treatment

Regulatory Complexity

Advanced Solutions for YourBusiness’s Toughest Challenges

Discover How We Help You Pay Only What You Owe—Nothing More

Frequently Asked Questions

Which activities typically qualify for R&D incentives in biotech, pharma, or device development?

How does Ryan help life sciences companies document and support their R&D claims?

How does Ryan support global entities with compliance for cross-border drug or device shipments?

The Power of Technology and Expertise—Working as One

Centralized technology tailored to your business

Dedicated experts aligned to performance goals

Real-time insights that drive better decisions

Single point of contact from start to finish

Simplified compliance across all jurisdictions

Manager, Taxes & Fixed Assets, Johnson & Johnson

Revenue and Reimbursement Complexity

Regulatory Burden

Data Accuracy and Systems Alignment

Multijurisdictional Compliance

R&D Incentives

Global Transfer Pricing

Commercialization and Revenue Treatment

Regulatory Complexity

Advanced Solutions for YourBusiness’s Toughest Challenges

Discover How We Help You Pay Only What You Owe—Nothing More

Frequently Asked Questions

Which activities typically qualify for R&D incentives in biotech, pharma, or device development?

How does Ryan help life sciences companies document and support their R&D claims?

How does Ryan support global entities with compliance for cross-border drug or device shipments?

Advanced Solutions for Your
Business’s Toughest Challenges

Advanced Solutions for Your
Business’s Toughest Challenges