Rare Disease Clinical Trials Programme
The Rare Disease Clinical Trials Programme is an open grant opportunity from LifeArc focused on advancing innovations for rare diseases through the clinical development pathway.

The Rare Disease Clinical Trials Programme is an open grant opportunity from LifeArc focused on advancing innovations for rare diseases through the clinical development pathway.

The Rare Disease Clinical Trials Programme is an open grant opportunity from LifeArc focused on advancing innovations for rare diseases through the clinical development pathway. The programme is intended to support clinical trial projects that can generate high-quality efficacy and safety data and help drive patient impact within the next 3–5 years.
Maximum award amount per project: Applicants can request up to £5 million per proposal.
Applications are open to the following applicant types:
Not-for-profit institutions
including academic institutes
healthcare organisations
public sector research establishments
SMEs
Applicants may be based in the UK or abroad.
The programme is designed to fund clinical trials for rare diseases that will generate high-quality efficacy and safety data and support clinical development of promising innovations.
Specifically, the programme supports early-stage clinical trials focused on proof of efficacy, with consideration of the route to patient impact within five years.
Eligible project types or interventions can include:
Therapeutics, including repurposed drugs
Advanced therapies, including gene and cell therapies
Medical technologies or devices
Diagnostics that demonstrate potential to improve decision-making and outcomes
Open for applications and proposals are reviewed on a rolling basis.
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